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Defence strategies: How immunology took its great leap forward

Defence strategies: How immunology took its great leap forward

作者:蓟牡卣  时间:2019-03-01 06:09:08  人气:

Science Photo Library By Jeremy Webb IMMUNOLOGIST Charles Janeway had an audacious idea. It was 1989 and most of his colleagues thought the immune system was primed solely to detect molecules it hadn’t seen before. Janeway thought he had evidence that novelty alone wasn’t enough to mobilise the body’s full defences. He proposed that a second signal was needed to tell if a foreign substance was a threat or not. That signal, he predicted, would come from cells pre-installed with receptors that lock onto specific molecules found on viruses,